Effect of a synthetic polypeptide (COP 1) on patients with multiple sclerosis and with acute disseminated encephalomyelitis: preliminary report

O Abramsky, D Teitelbaum, R Arnon - Journal of the neurological sciences, 1977 - Elsevier
Three patients with acute disseminated encephalomyelitis (ADE) and 4 patients in the
terminal stages of multiple sclerosis (MS) were subjected to treatment with Cop 1, a synthetic
copolymer of amino acids, which had previously been shown to have a beneficial effect in
the treatment of experimental allergic encephalomyelitis (EAE). Under the treatment, the
ADE patients recovered completely within 3 weeks, but 1 of 2 control cases treated with
steroids showed complete recovery as well. The MS patients did not show any significant …