Peptide and Major Histocompatibility Complex–Specific Breaking of Humoral Tolerance to Native Insulin With the B9-23 Peptide in Diabetes-Prone and Normal Mice
N Abiru, AK Maniatis, L Yu, D Miao, H Moriyama… - Diabetes, 2001 - Am Diabetes Assoc
NOD mice spontaneously develop anti-insulin autoantibodies and diabetes. A dominant
peptide recognized by T-cell clones from NOD mice is insulin B-chain peptide B9-23. When
administered subcutaneously to NOD mice, this peptide decreases the development of
diabetes. In this study, we evaluated the autoantibody response to native insulin after
administration of the B9-23 peptide. In NOD mice, administration of the B9-23 peptide in
incomplete Freund's adjuvant enhanced their insulin autoantibody response with a higher …
peptide recognized by T-cell clones from NOD mice is insulin B-chain peptide B9-23. When
administered subcutaneously to NOD mice, this peptide decreases the development of
diabetes. In this study, we evaluated the autoantibody response to native insulin after
administration of the B9-23 peptide. In NOD mice, administration of the B9-23 peptide in
incomplete Freund's adjuvant enhanced their insulin autoantibody response with a higher …
[CITATION][C] Peptide and MHC-Specific Breaking of Humoral Tolerance to Native Insulin with the B: 9-23 Peptide in Diabetes: Prone and Normal Mice
N Abiru - Diabetes, 2001 - cir.nii.ac.jp
Peptide and MHC-Specific Breaking of Humoral Tolerance to Native Insulin with the B : 9-23
Peptide in Diabetes : Prone and Normal Mice | CiNii Research CiNii 国立情報学研究所 学術
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Peptide in Diabetes : Prone and Normal Mice | CiNii Research CiNii 国立情報学研究所 学術
情報ナビゲータ[サイニィ] 詳細へ移動 検索フォームへ移動 論文・データをさがす 大学図書館の本を
さがす 日本の博士論文をさがす English 検索 タイトル 人物/団体名 所属機関 ISSN DOI 期間 ~
本文リンク 本文リンクあり データソース JaLC IRDB Crossref DataCite NDL NDL-Digital RUDA
JDCat NINJAL CiNii Articles CiNii Books CiNii Dissertations DBpedia Nikkei BP KAKEN …
