[HTML][HTML] The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein
F Alpy, ME Stoeckel, A Dierich, JM Escola… - Journal of Biological …, 2001 - ASBMB
MLN64 is a transmembrane protein that shares homology with the cholesterol binding
domain (START domain) of the steroidogenic acute regulatory protein. The steroidogenic
acute regulatory protein is located in the inner membrane of mitochondria, where it facilitates
cholesterol import into the mitochondria. Crystallographic analysis showed that the START
domain of MLN64 is a cholesterol-binding domain. The present work was undertaken to
determine which step of the intracellular cholesterol pathway MLN64 participates in. Using …
domain (START domain) of the steroidogenic acute regulatory protein. The steroidogenic
acute regulatory protein is located in the inner membrane of mitochondria, where it facilitates
cholesterol import into the mitochondria. Crystallographic analysis showed that the START
domain of MLN64 is a cholesterol-binding domain. The present work was undertaken to
determine which step of the intracellular cholesterol pathway MLN64 participates in. Using …