The origin of aortic phospholipid in rabbit atheromatosis

DB Zilversmit, ML SHORE, RF Ackerman - Circulation, 1954 - Am Heart Assoc
DB Zilversmit, ML SHORE, RF Ackerman
Circulation, 1954Am Heart Assoc
Radioactive phosphorus (P32) was injected into normal and cholesterol-fed rabbits. A
marked derangement of aortic phospholipid metabolism was found in the cholesterol-fed
animals. The phospholipid found in the atheromatous aortas appeared to have been
synthesized by the aorta itself rather than to have been deposited there from the plasma.
Radioactive phosphorus (P32) was injected into normal and cholesterol-fed rabbits. A marked derangement of aortic phospholipid metabolism was found in the cholesterol-fed animals. The phospholipid found in the atheromatous aortas appeared to have been synthesized by the aorta itself rather than to have been deposited there from the plasma.
Am Heart Assoc