Novel purification of vitronectin from human plasma by heparin affinity chromatography
T Yatohgo, M Izumi, H Kashiwagi… - Cell structure and …, 1988 - jstage.jst.go.jp
T Yatohgo, M Izumi, H Kashiwagi, M Hayashi
Cell structure and function, 1988•jstage.jst.go.jpThe glycoprotein vitronectin(also called S-protein, serum spreading factor, or epibolin)
promotes spreading of a variety of cultured cells, inhibits the cytotoxicity of membrane attack
complex C5b-9, and modulates thrombin-antithrombin III activity. We developed a strikingly
simple method to purify vitronectin from human plasma by heparin affinity chromatography.
promotes spreading of a variety of cultured cells, inhibits the cytotoxicity of membrane attack
complex C5b-9, and modulates thrombin-antithrombin III activity. We developed a strikingly
simple method to purify vitronectin from human plasma by heparin affinity chromatography.
Abstract
The glycoprotein vitronectin(also called S-protein, serum spreading factor, or epibolin) promotes spreading of a variety of cultured cells, inhibits the cytotoxicity of membrane attack complex C5b-9, and modulates thrombin-antithrombin III activity. We developed a strikingly simple method to purify vitronectin from human plasma by heparin affinity chromatography.
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