Background Studies in dogs showed that some hydroxymethylglutaryl coenzyme A
reductase inhibitors (statins) are associated with cataract when administered in excessive
doses. Clinical safety data of statins regarding cataract development in humans have been
of limited value so far. Objective To determine whether long-term use of statins is associated
with an increased risk of cataract. Methods We conducted a case-control analysis using data
from the United Kingdom–based General Practice Research Database. The main outcome …