Effect of leptin on the acute feeding-induced hypothalamic serotonergic stimulation in normal rats
MM Telles, RB Guimarães, EB Ribeiro - Regulatory peptides, 2003 - Elsevier
Both hypothalamic serotonin and leptin reduce energy intake and stimulate expenditure.
There are evidence that increased serotonin metabolism may be involved in leptin actions.
Using microdialysis, we directly assessed the effect of an intracerebroventricular leptin
injection on 5-HT release in the lateral hypothalamus of normal rats. When LH
microdialysates were collected in the absence of food intake, neither artificial cerebrospinal
fluid (CSF) nor 10 μg leptin icv caused significant variations in 5-HT release, measured for 2 …
There are evidence that increased serotonin metabolism may be involved in leptin actions.
Using microdialysis, we directly assessed the effect of an intracerebroventricular leptin
injection on 5-HT release in the lateral hypothalamus of normal rats. When LH
microdialysates were collected in the absence of food intake, neither artificial cerebrospinal
fluid (CSF) nor 10 μg leptin icv caused significant variations in 5-HT release, measured for 2 …
