Phosphatidylinositol-3-kinase signaling mediates vascular smooth muscle cell expression of periostin in vivo and in vitro
G Li, S Oparil, JM Sanders, L Zhang, M Dai, LB Chen… - Atherosclerosis, 2006 - Elsevier
OBJECTIVE: Periostin is dramatically upregulated in rat carotid arteries after balloon injury.
The objective of the present study was to understand mechanisms underlying periostin
upregulation in balloon-injured rat carotid arteries and in cultured vascular smooth muscle
cells (VSMCs). METHODS AND RESULTS: Periostin protein was strongly expressed at 3
days (in the medial SMCs) and 7 days (in the neointima) after injury. It was also abundantly
expressed in the neointima in the late phase (at 14 and 28 days) after injury. Periostin …
The objective of the present study was to understand mechanisms underlying periostin
upregulation in balloon-injured rat carotid arteries and in cultured vascular smooth muscle
cells (VSMCs). METHODS AND RESULTS: Periostin protein was strongly expressed at 3
days (in the medial SMCs) and 7 days (in the neointima) after injury. It was also abundantly
expressed in the neointima in the late phase (at 14 and 28 days) after injury. Periostin …
