Effect of sepsis on tissue adenine nucleotide levels
IH Chaudry, KA Wichterman, AE Baue - Surgery, 1979 - surgjournal.com
Tissue adenine nucleotides were measured in rats to determine if there is depletion of
energy stores associated with sepsis. Peritonitis was produced by cecal ligation and cecal
puncture. At 16 to 24 hours after ligation, rats which were lethargic but still normotensive
(late sepsis) and showed clinical and laboratory confirmation of peritonitis-sepsis were
stunned by a blow on the head, and small pieces of tissue were removed and frozen.
Adenine nucleotides were measured enzymatically. In late sepsis adenosine triphosphate …
energy stores associated with sepsis. Peritonitis was produced by cecal ligation and cecal
puncture. At 16 to 24 hours after ligation, rats which were lethargic but still normotensive
(late sepsis) and showed clinical and laboratory confirmation of peritonitis-sepsis were
stunned by a blow on the head, and small pieces of tissue were removed and frozen.
Adenine nucleotides were measured enzymatically. In late sepsis adenosine triphosphate …
