The natural history of lupus has changed dramatically since the 1970s not only because of
better treatments for systemic lupus erythematosus (SLE) but because of better supportive
measures, including antibiotics, better management of coronary artery disease, renal
dialysis, and renal transplantation. Lupus seems to have increased in its incidence and
prevalence since the 1970s. In a landmark study done in Rochester, Minnesota, Uramoto et
a P found that the incidence of lupus has tripled in the population, which is largely a middle …