The Human Proteome Organisation Human Disease Glycomics/Proteome Initiative recently
coordinated a multi-institutional study that evaluated methodologies that are widely used for
defining the N-glycan content in glycoproteins. The study convincingly endorsed mass
spectrometry as the technique of choice for glycomic profiling in the discovery phase of
diagnostic research. The present study reports the extension of the Human Disease
Glycomics/Proteome Initiative's activities to an assessment of the methodologies currently …