Macrophages associated with the intrinsic and extrinsic autonomic innervation of the rat gastrointestinal tract

RJ Phillips, TL Powley - Autonomic Neuroscience, 2012 - Elsevier
Interactions between macrophages and the autonomic innervation of gastrointestinal (GI)
tract smooth muscle have received little experimental attention. To better understand this
relationship, immunohistochemistry was performed on GI whole mounts from rats at three
ages. The phenotypes, morphologies, and distributions of gut macrophages are consistent
with the cells performing extensive housekeeping functions in the smooth muscle layers.
Specifically, a dense population of macrophages was located throughout the muscle wall …