[HTML][HTML] Delayed graft function in the kidney transplant

A Siedlecki, W Irish, DC Brennan - American journal of transplantation, 2011 - Elsevier
Acute kidney injury occurs with kidney transplantation and too frequently progresses to the
clinical diagnosis of delayed graft function (DGF). Poor kidney function in the first week of
graft life is detrimental to the longevity of the allograft. Challenges to understand the root
cause of DGF include several pathologic contributors derived from the donor (ischemic
injury, inflammatory signaling) and recipient (reperfusion injury, the innate immune response
and the adaptive immune response). Progressive demand for renal allografts has generated …