Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments

Y Kiuchi-Saishin, S Gotoh, M Furuse… - Journal of the …, 2002 - journals.lww.com
As the first step in understanding the physiologic functions of claudins (tight junction integral
membrane proteins) in nephrons, the expression of claudin-1 to-16 in mouse kidneys was
examined by Northern blotting. Among these claudins, only claudin-6,-9,-13, and-14 were
not detectable. Claudin-5 and-15 were detected only in endothelial cells. Polyclonal
antibodies specific for claudin-7 and-12 were not available. Therefore, the distributions of
claudin-1,-2,-3,-4,-8,-10,-11, and-16 in nephron segments were examined with …