[HTML][HTML] Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster

H Fyrst, DR Herr, GL Harris, JD Saba - Journal of lipid research, 2004 - ASBMB
Sphingolipid metabolites function as signaling molecules in mammalian cells, influencing
cell proliferation, migration, and death. Recently, sphingolipid signaling has been implicated
in the regulation of developmental processes in Drosophila melanogaster. However,
biochemical analysis of endogenous Drosophila sphingoid bases has not been reported. In
this study, a rapid HPLC-based method was developed for the analysis of free sphingoid
bases endogenous to Drosophila. Four molecular species of endogenous free sphingoid …