Pulmonary Lymphatics Are Primary Sites of Mycobacterium tuberculosis Infection in Guinea Pigs Infected by Aerosol
RJ Basaraba, EE Smith, CA Shanley… - Infection and …, 2006 - Am Soc Microbiol
RJ Basaraba, EE Smith, CA Shanley, IM Orme
Infection and Immunity, 2006•Am Soc MicrobiolMycobacterium tuberculosis causes a lymphatic vasculitis in the lungs of guinea pigs
infected by a low-dose aerosol. This observation suggests that in addition to being a direct
conduit from the lungs to the regional lymph nodes, pulmonary lymphatics are themselves
sites of infection and could be the site of latent infection.
infected by a low-dose aerosol. This observation suggests that in addition to being a direct
conduit from the lungs to the regional lymph nodes, pulmonary lymphatics are themselves
sites of infection and could be the site of latent infection.
Abstract
Mycobacterium tuberculosis causes a lymphatic vasculitis in the lungs of guinea pigs infected by a low-dose aerosol. This observation suggests that in addition to being a direct conduit from the lungs to the regional lymph nodes, pulmonary lymphatics are themselves sites of infection and could be the site of latent infection.
American Society for Microbiology