Deposits of IgG and C3 in the spinal cord and motor cortex of ALS patients
H Donnenfeld, RJ Kascsak, H Bartfeld - Journal of neuroimmunology, 1984 - Elsevier
Deposits of IgG and complement were demonstrated by direct immunofluorescent
techniques with sections of motor cortex and spinal cord from amyotrophic lateral sclerosis
(ALS) patients. Six of 16 ALS patients showed deposits within the spinal cord while 5 of 13
showed similar deposits within the motor cortex. The specificity of this staining was shown by
blocking experiments and the use of conjugated F (ab′) 2. Similar deposits were found in
the CNS in disease states associated with possible immune or infectious etiologies and …
techniques with sections of motor cortex and spinal cord from amyotrophic lateral sclerosis
(ALS) patients. Six of 16 ALS patients showed deposits within the spinal cord while 5 of 13
showed similar deposits within the motor cortex. The specificity of this staining was shown by
blocking experiments and the use of conjugated F (ab′) 2. Similar deposits were found in
the CNS in disease states associated with possible immune or infectious etiologies and …