[HTML][HTML] Heat-shock protein 90 alpha (HSP90α) modulates signaling pathways towards tolerance of oxidative stress and enhanced survival of hepatocytes of Mugil …
E Padmini, MU Rani - Cell Stress and Chaperones, 2011 - Elsevier
Oxidative stress causes damage at the cellular level and activates a number of signaling
pathways. Earlier, we have demonstrated that pollutant-related oxidative stress upregulates
heat-shock protein 90 alpha (HSP90α) against stress insult in hepatocytes of Mugil cephalus
living in a polluted estuary. However, the impact of pollution-induced HSP90α upregulation
on stress tolerance is not clear. Here we propose that the effect of stress resistance depends
on the ability of HSP90α to modulate the signaling pathways involving proteins such as …
pathways. Earlier, we have demonstrated that pollutant-related oxidative stress upregulates
heat-shock protein 90 alpha (HSP90α) against stress insult in hepatocytes of Mugil cephalus
living in a polluted estuary. However, the impact of pollution-induced HSP90α upregulation
on stress tolerance is not clear. Here we propose that the effect of stress resistance depends
on the ability of HSP90α to modulate the signaling pathways involving proteins such as …
