[HTML][HTML] Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases
N Mahrour, WB Redwine, L Florens… - Journal of Biological …, 2008 - ASBMB
The Elongin BC-box protein family includes the von Hippel-Lindau tumor suppressor and
suppressor of cytokine signaling proteins, which are substrate recognition subunits of
structurally related classes of E3 ubiquitin ligases composed of Elongin C-Elongin B-Cullin 2-
Rbx1 (Cul2 ubiquitin ligases) or of Elongin C-Elongin B-Cullin 5-Rbx2 (Cul5 ubiquitin
ligases). The Elongin BC complex acts as an adaptor that links a substrate recognition
subunit to heterodimers of either Cullin 2 (Cul2) and RING finger protein Rbx1 or Cullin 5 …
suppressor of cytokine signaling proteins, which are substrate recognition subunits of
structurally related classes of E3 ubiquitin ligases composed of Elongin C-Elongin B-Cullin 2-
Rbx1 (Cul2 ubiquitin ligases) or of Elongin C-Elongin B-Cullin 5-Rbx2 (Cul5 ubiquitin
ligases). The Elongin BC complex acts as an adaptor that links a substrate recognition
subunit to heterodimers of either Cullin 2 (Cul2) and RING finger protein Rbx1 or Cullin 5 …
