Nasopharyngeal bacterial burden and antibiotics: influence on inflammatory markers and disease severity in infants with respiratory syncytial virus bronchiolitis
MC Suárez-Arrabal, C Mella, SM Lopez, NV Brown… - Journal of Infection, 2015 - Elsevier
Objectives Animal studies suggest that RSV increases nasopharyngeal (NP) bacterial
colonization facilitating bacterial infections. We investigated the influence of antibiotic
treatment and colonization with potentially pathogenic bacteria on inflammatory markers and
disease severity in RSV-infected in infants. Methods Healthy young infants hospitalized with
RSV bronchiolitis (n= 136) and age-matched healthy controls (n= 23) were enrolled and NP
samples cultured for potentially pathogenic bacteria including: Gram-positive bacteria …
colonization facilitating bacterial infections. We investigated the influence of antibiotic
treatment and colonization with potentially pathogenic bacteria on inflammatory markers and
disease severity in RSV-infected in infants. Methods Healthy young infants hospitalized with
RSV bronchiolitis (n= 136) and age-matched healthy controls (n= 23) were enrolled and NP
samples cultured for potentially pathogenic bacteria including: Gram-positive bacteria …
