A method to generate antigen-specific mAb capable of staining formalin-fixed, paraffin-embedded tissue sections
X Wang, M Campoli, HS Cho, T Ogino… - Journal of …, 2005 - Elsevier
Abnormalities in HLA class I antigen expression are frequently found in malignant tumors.
Their potential role in the clinical course of the disease and in the outcome of T cell-based
immunotherapy has stimulated interest in the characterization of the molecular mechanisms
underlying HLA class I antigen abnormalities in malignant cells. Multiple mechanisms have
been identified. Among them are abnormalities in antigen processing machinery (APM)
component expression. In spite of this information, APM component expression in malignant …
Their potential role in the clinical course of the disease and in the outcome of T cell-based
immunotherapy has stimulated interest in the characterization of the molecular mechanisms
underlying HLA class I antigen abnormalities in malignant cells. Multiple mechanisms have
been identified. Among them are abnormalities in antigen processing machinery (APM)
component expression. In spite of this information, APM component expression in malignant …
