Aspects of immune dysfunction in end-stage renal disease
S Kato, M Chmielewski, H Honda… - Clinical Journal of the …, 2008 - journals.lww.com
End-stage renal disease (ESRD) is associated with significantly increased morbidity and
mortality resulting from cardiovascular disease (CVD) and infections, accounting for 50%
and 20%, respectively, of the total mortality in ESRD patients. It is possible that these two
complications are linked to alterations in the immune system in ESRD, as uremia is
associated with a state of immune dysfunction characterized by immunodepression that
contributes to the high prevalence of infections among these patients, as well as by …
mortality resulting from cardiovascular disease (CVD) and infections, accounting for 50%
and 20%, respectively, of the total mortality in ESRD patients. It is possible that these two
complications are linked to alterations in the immune system in ESRD, as uremia is
associated with a state of immune dysfunction characterized by immunodepression that
contributes to the high prevalence of infections among these patients, as well as by …