Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients
M Cowan, WJ Chon, A Desai, S Andrews, Y Bai… - …, 2014 - journals.lww.com
M Cowan, WJ Chon, A Desai, S Andrews, Y Bai, V Veguilla, JM Katz, MA Josephson…
Transplantation, 2014•journals.lww.comBackground The recommendation by the American Society of Transplantation for annual
trivalent inactivated influenza vaccination greater than 3 to 6 months post-kidney
transplantation provides a unique opportunity to test the in vivo impact of
immunosuppression on recall T-and B-cell responses to influenza vaccination. Methods This
study took advantage of recent breakthroughs in the single-cell quantification of human
peripheral blood B-cell responses to prospectively evaluate both B-and T-cell responses to …
trivalent inactivated influenza vaccination greater than 3 to 6 months post-kidney
transplantation provides a unique opportunity to test the in vivo impact of
immunosuppression on recall T-and B-cell responses to influenza vaccination. Methods This
study took advantage of recent breakthroughs in the single-cell quantification of human
peripheral blood B-cell responses to prospectively evaluate both B-and T-cell responses to …
Abstract
Background
The recommendation by the American Society of Transplantation for annual trivalent inactivated influenza vaccination greater than 3 to 6 months post-kidney transplantation provides a unique opportunity to test the in vivo impact of immunosuppression on recall T-and B-cell responses to influenza vaccination.
Methods
This study took advantage of recent breakthroughs in the single-cell quantification of human peripheral blood B-cell responses to prospectively evaluate both B-and T-cell responses to the seasonal (2010 and 2011) influenza vaccine in 23 stable renal transplant recipients and 22 healthy controls.
Lippincott Williams & Wilkins