The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is
thought to develop as a result of interactions between environmental, microbial, and immune-
mediated factors in a genetically susceptible host. Of late, the potential role of the
microbiome in the development, progression, and treatment of IBD has been a subject of
considerable interest and enquiry. Indeed, studies in human subjects have shown that the …