Effect of kisspeptin on the proliferation and apoptosis of bovine granulosa cells

H Liu, G Xu, Z Yuan, Y Dong, J Wang, W Lu - Animal reproduction science, 2017 - Elsevier
Previous studies have shown that kisspeptin (Kp-10) is expressed in mammalian ovaries;
however, the expression and role of Kp-10 in bovine ovarian granulosa cells are still
unclear. In this study, we assessed the expression of Kp-10 and its effects on the
proliferation and apoptosis of bovine granulosa cells. Immunohistochemical analysis
showed that Kp-10 was expressed in the cytoplasm of bovine ovarian granulosa cells.
Moreover, MTT assays showed that 100 nM Kp-10 significantly inhibited the viability of …