Deregulation of miR-324/KISS1/kisspeptin in early ectopic pregnancy: mechanistic findings with clinical and diagnostic implications
A Romero-Ruiz, MS Avendaño, F Dominguez… - American Journal of …, 2019 - Elsevier
Background Ectopic pregnancy is a life-threatening condition for which novel screening
tools that would enable early accurate diagnosis would improve clinical outcomes.
Kisspeptins, encoded by KISS1, play an essential role in human reproduction, at least
partially by regulating placental function and possibly embryo implantation. Kisspeptin levels
are elevated massively in normal pregnancy and reportedly altered in various gestational
pathologic diseases. Yet, the pathophysiologic role of KISS1/kisspeptin in ectopic pregnancy …
tools that would enable early accurate diagnosis would improve clinical outcomes.
Kisspeptins, encoded by KISS1, play an essential role in human reproduction, at least
partially by regulating placental function and possibly embryo implantation. Kisspeptin levels
are elevated massively in normal pregnancy and reportedly altered in various gestational
pathologic diseases. Yet, the pathophysiologic role of KISS1/kisspeptin in ectopic pregnancy …