[PDF][PDF] Macrophage-tumor cell intertwine drives the transition into a mesenchymal-like cellular state of glioblastoma

Z Chen, D Hambardzumyan - Cancer Cell, 2021 - cell.com
Cancer Cell, 2021cell.com
Macrophages are the major non-neoplastic infiltrates in the glioblastoma microenvironment.
In this issue of Cancer Cell, Hara et al.(2021) demonstrate that macrophages induce a
transition of glioblastoma cells into the mesenchymal-like cellular state associated with an
increased mesenchymal program in macrophages themselves and enhanced cytotoxicity of
T cells.
Macrophages are the major non-neoplastic infiltrates in the glioblastoma microenvironment. In this issue of Cancer Cell, Hara et al. (2021) demonstrate that macrophages induce a transition of glioblastoma cells into the mesenchymal-like cellular state associated with an increased mesenchymal program in macrophages themselves and enhanced cytotoxicity of T cells.
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