Adoptive transfer of HHD-derived anti–BA46-specific CTLs to MDA-MB-231 tumor-bearing CD1nu/nu mice. CTLs specific to BA46 peptides were obtained from HHD mice and adoptively transferred to CD1nu/nu MDA-MB-231 tumor-bearing mice (eight mice per group) as described in Methods. Tumor growth was followed for 40 days. CTLs from mice immunized with unloaded RMA-S-HHD-B7.1 (seven mice per group) and RMA-S-HHD-B7.1 loaded with unrelated HIV TAX-derived peptide (four mice per group) are the negative controls in the experiment. The experiment was performed once. For statistical analysis see text.